CMET-26. IN-VITRO & IN-VIVO CULTURE OF PATIENT (PT) DERIVED CSF-CTCS IN LEPTOMENINGEAL DISEASE (LMDZ) FROM MELANOMA TO IDENTIFY NOVEL TREATMENT STRATEGIES

BACKGROUND: Approx. 5% of melanoma pts develop LMDz. There are essentially no models of LMDz available for therapeutic development. Here we report, the in-vitro & in-vivo culturing of CSF-CTCs. METHODS: CSF-CTCs were detected by the Veridex CellSearch® System. Cell-free DNA and cell-associated D...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Law, Vincent, Evernden, Brittany, Puskas, John, Caceres, Gisela, Ryzhova, Elena, Smalley, Inna, Tran, Nam, Etame, Arnold, Sahebjam, Solmaz, Magliocco, Anthony, Smalley, Keiran, Forsyth, Peter
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
CNS Metastasis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847982/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.227
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