GENE-39. CRISPRi-BASED RADIATION MODIFIER SCREEN IDENTIFIES LONG NON-CODING RNA THERAPEUTIC TARGETS IN GLIOMA

Long noncoding RNAs (lncRNAs) exhibit highly cell type-specific expression and function, making this class of transcript attractive for targeted cancer therapy. However, the vast majority of lncRNAs have not been tested as potential therapeutic targets, particularly in the context of currently used...

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Vydáno v:Neuro Oncol
Hlavní autoři: John Liu, S, Malatesta, Martina, Seo, Kyounghee, Lien, Brian, Hong, Sung, Koontz, Mark, Raleigh, David, Ullian, Erik, Lim, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Genetics and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847918/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.441
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