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GENE-39. CRISPRi-BASED RADIATION MODIFIER SCREEN IDENTIFIES LONG NON-CODING RNA THERAPEUTIC TARGETS IN GLIOMA

Long noncoding RNAs (lncRNAs) exhibit highly cell type-specific expression and function, making this class of transcript attractive for targeted cancer therapy. However, the vast majority of lncRNAs have not been tested as potential therapeutic targets, particularly in the context of currently used...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Principais autores: John Liu, S, Malatesta, Martina, Seo, Kyounghee, Lien, Brian, Hong, Sung, Koontz, Mark, Raleigh, David, Ullian, Erik, Lim, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847918/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.441
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