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PDTM-08. SINGLE-CELL GENOMICS REVEALS TUMOR-INITIATING PROGENITORS AND ONCOGENIC CASCADES DURING TUMORIGENESIS AND RELAPSE IN MEDULLOBLASTOMA

Progenitor heterogeneity and identities underlying tumor initiation and relapse in medulloblastomas, the most common malignant pediatric brain tumor, remain elusive. Here, by utilizing single-cell analysis at different stages of tumorigenesis, we demonstrated a developmental hierarchy of diverse pro...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Zhang, Liguo, He, Xuelian, Liu, Xuezhao, Berry, Kalen, Lu, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847861/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.784
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