PDTM-08. SINGLE-CELL GENOMICS REVEALS TUMOR-INITIATING PROGENITORS AND ONCOGENIC CASCADES DURING TUMORIGENESIS AND RELAPSE IN MEDULLOBLASTOMA

Progenitor heterogeneity and identities underlying tumor initiation and relapse in medulloblastomas, the most common malignant pediatric brain tumor, remain elusive. Here, by utilizing single-cell analysis at different stages of tumorigenesis, we demonstrated a developmental hierarchy of diverse pro...

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發表在:Neuro Oncol
Main Authors: Zhang, Liguo, He, Xuelian, Liu, Xuezhao, Berry, Kalen, Lu, Richard
格式: Artigo
語言:Inglês
出版: Oxford University Press 2019
主題:
Pediatric Tumors
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847861/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.784
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