EXTH-21. DIFFERENTIAL PROTEIN EXPRESSION LEVELS OF ABC AND SOLUTE CARRIER TRANSPORTERS AT THE BLOOD-BRAIN BARRIER OF HUMAN BRAIN AND GLIOBLASTOMA

BACKGROUND: Mechanistic understanding and quantitative prediction of drug penetration across the human blood-brain barrier (BBB) is critical to rational drug development and treatment for brain cancer especially glioblastoma. However, prediction of drug brain/tumor penetration has been significantly...

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Publicado en:Neuro Oncol
Main Authors: Bao, Xun, Wu, Jianmei, Xie, Youming, Kim, Seongho, Michelhaugh, Sharon, Jiang, Jun, Mittal, Sandeep, Sanai, Nader, Li, Jing
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Experimental Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847747/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.355
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