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EXTH-33. VALPROIC ACID ENHANCES THE ANTI-PROLIFERATIVE EFFECT OF TUMOR-TREATING FIELDS ON PATIENT-DERIVED GLIOSARCOMA CELLS IN VITRO

BACKGROUND: Valproic acid (VPA) is an anti-epileptic drug often prescribed for glioma-associated seizures. VPA is also investigated as a potential anti-proliferative cancer treatment due to its histone deacetylase inhibitor activity. Tumor-treating fields (TTFields) are an FDA-approved therapy that...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Michelhaugh, Sharon, Mittal, Sandeep
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651683/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.387
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