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Protein Expression and Functional Relevance of Efflux and Uptake Drug Transporters at the Blood-Brain Barrier of Human Brain and Glioblastoma

The knowledge of transporter protein expression and function at the human blood-brain barrier (BBB) is critical to prediction of drug BBB penetration and design of strategies for improving drug brain/brain tumor delivery. This study determined absolute transporter protein abundances in isolated micr...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Bao, Xun, Wu, Jianmei, Xie, Youming, Kim, Seongho, Michelhaugh, Sharon, Jiang, Jun, Mittal, Sandeep, Sanai, Nader, Li, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7167337/
https://ncbi.nlm.nih.gov/pubmed/31664714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1710
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