GENE-45. DISSECTING THE DRIVERS OF ADULT H3K27M-GLIOMAS AT THE SINGLE-CELL LEVEL

Diffuse midline gliomas are characterized by a lysine27-to-methionine mutation in histone H3 (H3K27M-glioma) and represent a highly aggressive molecular entity of high-grade gliomas. These mutations have primarily been described in children, but are also increasingly recognized in adults. In pediatr...

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Publicat a:Neuro Oncol
Autors principals: Liu, Ilon, Avihai, Byron, Gojo, Johannes, Ligon, Keith, Czech, Thomas, Slavc, Irene, Kleinman, Claudia, Jabado, Nada, Filbin, Mariella
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Genetics and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847648/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.447
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