EXTH-12. RADIATION ENHANCES MELANOMA RESPONSE TO IMMUNOTHERAPY AND SYNERGIZES WITH BENZODIAZEPINES TO PROMOTE ANTI-TUMOR ACTIVITY

Melanoma brain metastases (MBM) occur in ~50% of advanced melanoma patients. It is unclear if systemic therapies synergize with radiotherapy (RT) and what the impact of RT timing has on efficacy. We find that RT followed by ICI (immune checkpoint inhibitors) (RTàICI) improves MBM patient survival co...

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Bibliografische gegevens
Gepubliceerd in:Neuro Oncol
Hoofdauteurs: Pomeranz Krummel, Daniel, Nasti, Tahseen, Izar, Benjamin, Xu, Maxwell, Lowder, Lindsey, Press, Robert, Kaluzova, Milota, Kallay, Laura, Rupji, Manali, Burnham, Andre, Li, Guanguan, Ahmed, Taukir, Rosen, Havi, Connolly, Erin, Keskin, Havva, Ben Thomas, Midhun, Curran, Walter, Kudchadkar, Ragini, Weinberg, Brent, Olson, Jeffrey, Schniederjan, Matthew, Neil, Stewart, Su, Jing, Lawson, David, Cook, James, Jenkins, Andrew, Kowalski, Jeanne, Khan, Mohammad, Sengupta, Soma
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
Onderwerpen:
Experimental Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847525/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.346
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