QOLP-04. CALCULATING THE NET CLINICAL BENEFIT IN BRAIN TUMOR TRIALS BY COMBINING SURVIVAL AND HEALTH-RELATED QUALITY OF LIFE DATA USING TWO METHODS: QUALITY ADJUSTED SURVIVAL EFFECT SIZES AND JOINT MODELLING

INTRODUCTION: The impact of treatment on both the quality and the quantity of life, i.e. the ‘net clinical benefit’, should be considered to facilitate shared decision making. Two methods that combine survival and health-related quality of life (HRQoL) data: Quality Adjusted Effect Sizes (QASES) and...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Coomans, Marijke, Dirven, Linda, Bottomley, Andrew, van den Bent, Martin, Sloan, Jeff, Stupp, Roger, Weller, Michael, Reijneveld, Jaap, Taphoorn, Martin, Aaronson, Neil, Baumert, Brigitta, Brandes, Alba, Chinot, Olivier, Coens, Corneel, Gorlia, Thierry, Herrlinger, Ulrich, Keime-Guibert, Florence, Malmström, Annika, Martinelli, Francesca, Talacchi, Andrea, Wick, Wolfgang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Quality of Life and Palliative Care
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847512/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.824
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