OS7.4 Calculating the net clinical benefit in brain tumor clinical trials by combining survival and health-related quality of life data using two methods: quality adjusted survival effect sizes (QASES) and joint modelling (JM)

BACKGROUND: The impact of treatment on both the quality and the quantity of life, i.e. the ‘net clinical benefit’, should be considered to inform glioma patients and facilitate shared decision making. We applied two methods (i.e. Quality Adjusted Effect Sizes (QASES) and Joint Modelling (JM)) that c...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Coomans, M, Dirven, L, Bottomley, A, van den Bent, M, Sloan, J, Stupp, R, Weller, M, Reijneveld, J C, Taphoorn, M, Aaronson, N, Baumert, B G, Brandes, A A, Chinot, O, Coens, C, Gorlia, T, Herrlinger, U, Keime-Guibert, F, Malmström, A, Martinelli, F, Talacchi, A, Wick, W
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Oral Presentations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795111/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.047
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