OS7.4 Calculating the net clinical benefit in brain tumor clinical trials by combining survival and health-related quality of life data using two methods: quality adjusted survival effect sizes (QASES) and joint modelling (JM)

BACKGROUND: The impact of treatment on both the quality and the quantity of life, i.e. the ‘net clinical benefit’, should be considered to inform glioma patients and facilitate shared decision making. We applied two methods (i.e. Quality Adjusted Effect Sizes (QASES) and Joint Modelling (JM)) that c...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Coomans, M, Dirven, L, Bottomley, A, van den Bent, M, Sloan, J, Stupp, R, Weller, M, Reijneveld, J C, Taphoorn, M, Aaronson, N, Baumert, B G, Brandes, A A, Chinot, O, Coens, C, Gorlia, T, Herrlinger, U, Keime-Guibert, F, Malmström, A, Martinelli, F, Talacchi, A, Wick, W
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Oral Presentations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795111/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.047
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