DDIS-32. MEK INHIBITORS INDUCES NEURONAL DIFFERENTIATION IN EGFR AMPLIFIED GLIOMA STEM LIKE CELLS

The median survival for patients with glioblastoma (GBM) is 12–15 months highlighting the need for better therapeutic strategies for this deadly disease. Genomic and epigenomic sequencing analysis at the single cell level have identified multiple genomic aberrations as potential targets for therapeu...

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Podrobná bibliografie
Vydáno v:Neuro Oncol
Hlavní autoři: Balasubramaniyan, Veerakumar, Park, Soon, Piao, Yuji, Martínez, Emmanuel, Dong, Jianwen, Mittal, Sandeep, Khan, Sabbir, Zhang, Ze-yan, Sulman, Erik, DeGroot, John
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Drug Discovery
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847454/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.283
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