DDIS-32. MEK INHIBITORS INDUCES NEURONAL DIFFERENTIATION IN EGFR AMPLIFIED GLIOMA STEM LIKE CELLS

The median survival for patients with glioblastoma (GBM) is 12–15 months highlighting the need for better therapeutic strategies for this deadly disease. Genomic and epigenomic sequencing analysis at the single cell level have identified multiple genomic aberrations as potential targets for therapeu...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Balasubramaniyan, Veerakumar, Park, Soon, Piao, Yuji, Martínez, Emmanuel, Dong, Jianwen, Mittal, Sandeep, Khan, Sabbir, Zhang, Ze-yan, Sulman, Erik, DeGroot, John
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Drug Discovery
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847454/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.283
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