STEM-21. INVESTIGATING DOT1L AS AN EPIGENETIC VULNERABILITY IN BRAIN TUMOR STEM CELLS

Glioblastoma (GBM), the most common and aggressive primary adult brain cancer, is thought to be driven by a small subpopulation of brain tumor stem cells (BTSCs). BTSCs exhibit shared properties with normal stem cells such as self-renewal and multilineage differentiation. These stem cell properties...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Bozek, Danielle, MacLeod, Graham, Hao, Xiaoguang, Rajakulendran, Nishani, Ahmadi, Moloud, Dirks, Peter, Angers, Stephane, Luchman, Artee, Weiss, Sam
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847418/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.994
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