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EXTH-36. PI3K INHIBITION IN CONJUNCTION WITH THE KETOGENIC DIET REDUCES GROWTH AND NEUROINFLAMMATION IN PEDIATRIC HIGH-GRADE GLIOMA

Pediatric high-grade glioma remains a poorly treatable disease with high mortality. Targeted therapies have gained interest in this disease, but efficacy is limited by therapeutic resistance, often because of tumor heterogeneity. Phosphoinositide 3-kinase (PI3K) inhibitors represent a strong drug cl...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Noch, Evan, Yim, Isaiah, Cantley, Lewis
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847406/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.368
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