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P11.63 PI3K inhibition in conjunction with the ketogenic diet reduces growth and neuroinflammation in pediatric high-grade glioma

Background: Pediatric high-grade glioma remains a poorly treatable disease with high mortality.Therapeutic advances have lagged behind that of adult glioblastoma, due to small patient numbers, inappropriate generalization from adult tumor types, and unique biology. The use of targeted therapy has re...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Noch, E, Yim, I, Cantley, L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796179/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.209
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