IMMU-28. TARGETING IMMUNOSUPPRESSIVE MYELOID DERIVED SUPPRESSOR CELLS VIA MIF/CD74 SIGNALING AXIS TO ATTENUATE GBM GROWTH

The immunosuppressive microenvironment in glioblastoma (GBM) enables persistent tumor growth and evasion from tumoricidal immune cell recognition. Despite a large accumulation of immune cells in the GBM microenvironment, tumor growth continues, and evidence for potent immunosuppression via myeloid d...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Alban, Tyler, Bayik, Defne, Otvos, Balint, Grabowski, Matthew, Ahluwalia, Manmeet, Bucala, Richard, Vogelbaum, Michael, Lathia, Justin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847354/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.521
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