THE ROLE OF MYELOID DERIVED SUPPRESSOR CELLS (MDSCS) IN TUMOR-INDUCED IMMUNOSUPPRESSION IN HUMAN AND MURINE GLIOMAS

BACKGROUND: (blind field) METHODS: To further study the biology of MDSCs in GBM, we have evaluated two preclinical models of GBM (RCAS tVA, GL261 orthografts) and observed a similar magnitude of glioma-induced elevation of circulating MDSCs as we observed in GBM patients. RESULTS: With use of immuno...

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書誌詳細
主要な著者: Vogelbaum, Michael A., Otvos, Balint, Raychaudhuri, Baisakhi, Hambardzumyan, Dolores, Finke, James, Lathia, Justin
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
abstracts
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144623/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou209.10
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