Immunosuppression mediated by myeloid-derived suppressor cells (MDSCs) during tumour progression

Under steady-state conditions, bone marrow-derived immature myeloid cells (IMC) differentiate into granulocytes, macrophages and dendritic cells (DCs). This differentiation is impaired under chronic inflammatory conditions, which are typical for tumour progression, leading to the accumulation of IMC...

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Bibliographic Details
Published in:Br J Cancer
Main Authors: Groth, Christopher, Hu, Xiaoying, Weber, Rebekka, Fleming, Viktor, Altevogt, Peter, Utikal, Jochen, Umansky, Viktor
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325125/
https://ncbi.nlm.nih.gov/pubmed/30413826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0333-1
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