Immunosuppression mediated by myeloid-derived suppressor cells (MDSCs) during tumour progression

Under steady-state conditions, bone marrow-derived immature myeloid cells (IMC) differentiate into granulocytes, macrophages and dendritic cells (DCs). This differentiation is impaired under chronic inflammatory conditions, which are typical for tumour progression, leading to the accumulation of IMC...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Br J Cancer
Main Authors: Groth, Christopher, Hu, Xiaoying, Weber, Rebekka, Fleming, Viktor, Altevogt, Peter, Utikal, Jochen, Umansky, Viktor
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Review Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325125/
https://ncbi.nlm.nih.gov/pubmed/30413826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0333-1
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