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Detection of internal N7-methylguanosine (m(7)G) RNA modifications by mutational profiling sequencing

Methylation of guanosine on position N7 (m(7)G) on internal RNA positions has been found in all domains of life and have been implicated in human disease. Here, we present m(7)G Mutational Profiling sequencing (m(7)G-MaP-seq), which allows high throughput detection of m(7)G modifications at nucleoti...

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Publicat a:Nucleic Acids Res
Autors principals: Enroth, Christel, Poulsen, Line Dahl, Iversen, Søren, Kirpekar, Finn, Albrechtsen, Anders, Vinther, Jeppe
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847341/
https://ncbi.nlm.nih.gov/pubmed/31504776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz736
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