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Detection of internal N7-methylguanosine (m(7)G) RNA modifications by mutational profiling sequencing

Methylation of guanosine on position N7 (m(7)G) on internal RNA positions has been found in all domains of life and have been implicated in human disease. Here, we present m(7)G Mutational Profiling sequencing (m(7)G-MaP-seq), which allows high throughput detection of m(7)G modifications at nucleoti...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Enroth, Christel, Poulsen, Line Dahl, Iversen, Søren, Kirpekar, Finn, Albrechtsen, Anders, Vinther, Jeppe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847341/
https://ncbi.nlm.nih.gov/pubmed/31504776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz736
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