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ACTR-55. OPTIMIZED TREAT-RESECT-TREAT STUDY DESIGN FOR CONVECTION-ENHANCED DELIVERY OF A FIRST-IN-CLASS BIOLOGIC IN THE TREATMENT OF GLIOBLASTOMA

INTRODUCTION: Development of effective treatments for high-grade glioma (HGG) including glioblastoma is hampered by 1) the blood brain barrier, 2) an infiltrative growth pattern, 3) rapid development of adaptive therapeutic resistance, and 4) dose-limiting toxicity due to systemic exposure. Novel th...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Immidisetti, Amanda, Nwagwu, Chibueze, Shawn Carbonell, W, Carbonell, Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847271/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.097
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