Convection Enhanced Delivery in the Setting of High-Grade Gliomas

Development of effective treatments for high-grade glioma (HGG) is hampered by (1) the blood–brain barrier (BBB), (2) an infiltrative growth pattern, (3) rapid development of therapeutic resistance, and, in many cases, (4) dose-limiting toxicity due to systemic exposure. Convection-enhanced delivery...

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Bibliografiske detaljer
Udgivet i:Pharmaceutics
Main Authors: Nwagwu, Chibueze D., Immidisetti, Amanda V., Jiang, Michael Y., Adeagbo, Oluwasegun, Adamson, David C., Carbonell, Anne-Marie
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8071501/
https://ncbi.nlm.nih.gov/pubmed/33921157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13040561
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