ATIM-30. COMBATING RECURRENT GLIOBLASTOMA WITH MDNA55, AN INTERLEUKIN-4 RECEPTOR TARGETED IMMUNOTHERAPY, THROUGH MRI-GUIDED CONVECTIVE DELIVERY

MDNA55, an IL4R-directed toxin, is being studied in a Phase 2b trial in recurrent GBM (rGBM) patients at first or second relapse. MDNA55 is co-infused with Gadolinium-based contrast agent and delivered as a single intratumoral infusion using Convection Enhanced Delivery (CED). Primary endpoint is me...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Sampson, John, Singh Achrol, Achal, Aghi, Manish, Bankiewicz, Krystof, Brem, Steven, Brenner, Andrew, Butowski, Nicholas, Chandhasin, Chandtip, Chowdhary, Sajeel, Coello, Melissa, Floyd, John R, Kesari, Santosh, Merchant, Fahar, Merchant, Nina, Randazzo, Dina, Vogelbaum, Michael, Vrionis, Frank, Zabek, Miroslaw, Bexon, Martin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Adult Clinical Trials–Immunologic
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847825/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.029
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