ATIM-30. COMBATING RECURRENT GLIOBLASTOMA WITH MDNA55, AN INTERLEUKIN-4 RECEPTOR TARGETED IMMUNOTHERAPY, THROUGH MRI-GUIDED CONVECTIVE DELIVERY

MDNA55, an IL4R-directed toxin, is being studied in a Phase 2b trial in recurrent GBM (rGBM) patients at first or second relapse. MDNA55 is co-infused with Gadolinium-based contrast agent and delivered as a single intratumoral infusion using Convection Enhanced Delivery (CED). Primary endpoint is me...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Sampson, John, Singh Achrol, Achal, Aghi, Manish, Bankiewicz, Krystof, Brem, Steven, Brenner, Andrew, Butowski, Nicholas, Chandhasin, Chandtip, Chowdhary, Sajeel, Coello, Melissa, Floyd, John R, Kesari, Santosh, Merchant, Fahar, Merchant, Nina, Randazzo, Dina, Vogelbaum, Michael, Vrionis, Frank, Zabek, Miroslaw, Bexon, Martin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2019
Pynciau:
Adult Clinical Trials–Immunologic
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847825/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.029
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