ATIM-16. MRI-GUIDED CONVECTIVE DELIVERY OF MDNA55, AN INTERLEUKIN-4 RECEPTOR TARGETED IMMUNOTHERAPY FOR THE TREATMENT OF RECURRENT GLIOBLASTOMA

Intratumoral glioblastoma therapy has been limited by suboptimal spatial distribution of therapeutic agents. MR-guided convection-enhanced delivery (CED) of MDNA-55 (interleukin-4 fused to Pseudomonasexotoxin) is underway in a Phase 2 open-label study in up to 43 patients with recurrent glioblastoma...

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Publicat a:Neuro Oncol
Autors principals: Bankiewicz, Krystof, Achrol, Achal, Aghi, Manish, Bexon, Martin, Brenner, Andrew, Butowski, Nicholas, Elder, Bradley, Floyd, John, Lonser, Russell, Merchant, Fahar, Rosemina, Merchant, Patel, Toral R, Randazzo, Dina, Souweidane, Mark, Vogelbaum, Michael, Vrionis, Frank D, Sampson, John
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Abstracts
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692114/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.111
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