IMMU-13. MECHANISMS OF IMMUNOLOGICAL ESCAPE DURING ADOPTIVE CELLULAR THERAPY IN HIGH GRADE GLIOMA

INTRODUCTION: Immunotherapy is remarkably effective, yet tumor escape is common. Herein, we investigated tumor escape after adoptive cellular therapy (ACT) in intractable glioma models. These studies revealed multiple mechanisms of escape including a shift in immunogenic tumor antigens, downregulati...

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發表在:Neuro Oncol
Main Authors: Wildes, Tyler, Dyson, Kyle, Francis, Connor, Wummer, Brandon, Yang, Changlin, Yegorov, Oleg, Shin, David, Grippin, Adam, Divita, Bayli, Mitchell, Duane, Flores, Catherine
格式: Artigo
語言:Inglês
出版: Oxford University Press 2019
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847152/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.507
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