IMMU-13. MECHANISMS OF IMMUNOLOGICAL ESCAPE DURING ADOPTIVE CELLULAR THERAPY IN HIGH GRADE GLIOMA

INTRODUCTION: Immunotherapy is remarkably effective, yet tumor escape is common. Herein, we investigated tumor escape after adoptive cellular therapy (ACT) in intractable glioma models. These studies revealed multiple mechanisms of escape including a shift in immunogenic tumor antigens, downregulati...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Wildes, Tyler, Dyson, Kyle, Francis, Connor, Wummer, Brandon, Yang, Changlin, Yegorov, Oleg, Shin, David, Grippin, Adam, Divita, Bayli, Mitchell, Duane, Flores, Catherine
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847152/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.507
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