IMMU-13. MECHANISMS OF IMMUNOLOGICAL ESCAPE DURING ADOPTIVE CELLULAR THERAPY IN HIGH GRADE GLIOMA

INTRODUCTION: Immunotherapy is remarkably effective, yet tumor escape is common. Herein, we investigated tumor escape after adoptive cellular therapy (ACT) in intractable glioma models. These studies revealed multiple mechanisms of escape including a shift in immunogenic tumor antigens, downregulati...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Wildes, Tyler, Dyson, Kyle, Francis, Connor, Wummer, Brandon, Yang, Changlin, Yegorov, Oleg, Shin, David, Grippin, Adam, Divita, Bayli, Mitchell, Duane, Flores, Catherine
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847152/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.507
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