IMMU-13. MECHANISMS OF IMMUNOLOGICAL ESCAPE DURING ADOPTIVE CELLULAR THERAPY IN HIGH GRADE GLIOMA

INTRODUCTION: Immunotherapy is remarkably effective, yet tumor escape is common. Herein, we investigated tumor escape after adoptive cellular therapy (ACT) in intractable glioma models. These studies revealed multiple mechanisms of escape including a shift in immunogenic tumor antigens, downregulati...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Wildes, Tyler, Dyson, Kyle, Francis, Connor, Wummer, Brandon, Yang, Changlin, Yegorov, Oleg, Shin, David, Grippin, Adam, Divita, Bayli, Mitchell, Duane, Flores, Catherine
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847152/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.507
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