PDTM-05. SONIC HEDGEHOG SIGNALING PRIMES CEREBELLAR GRANULE NEURON PROGENITORS AND MEDULLOBLASTOMA CELLS FOR APOPTOSIS BY INDUCING PRO-APOPTOTIC BIM

Medulloblastomas, unlike other malignant brain tumors, are typically sensitive to radiation therapy (xRT). However, although xRT allows medulloblastoma patients to survive, it can also confer significant long term cognitive sequelae. Understanding the mechanisms of radiation sensitivity in medullobl...

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Vydáno v:Neuro Oncol
Hlavní autoři: Cleveland, Abigail, Veleta, Katherine, Gershon, Timothy
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Pediatric Tumors
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847084/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.781
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