DRES-10. TEMOZOLOMIDE-ASSOCIATED HYPERMUTATION DETECTED WITH A GENE PANEL SIGNATURE IMPROVES IMMUNE RESPONSE IN GLIOBLASTOMA

Glioblastoma (GBM) is the most common and deadly type of malignant brain cancer in adults. While current standard of care which combines resection, radiation therapy (RT) and Temozolomide (TMZ) effectively eliminates primary disease, recurrence is inevitable, occurs rapidly following treatment and i...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Daniel, Paul, Meehan, Brian, Sabri, Siham, Sarkaria, Jann, Rak, Janusz, Abdulkarim, Bassam
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Drug Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846891/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.298
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