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SCIDOT-15. DISRUPTING THE BLOOD-BRAIN BARRIER IN NEURO-ONCOLOGY: INNOVATIONS, ACHIEVEMENTS, AND LESSONS LEARNED FROM CLINICAL TRIALS

BACKGROUND: The blood-brain barrier (BBB) presents a formidable challenge for the development of effective therapeutics in neuro-oncology. Several strategies for the disruption of the BBB have been investigated in humans. An in-depth analysis of the concepts, design, and outcomes from these trials c...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Philtheos, Justine, Abbasian, Aram, Karmur, Brij, Mansouri, Alireza
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846789/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1151
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