Blood-Brain Barrier Disruption in Neuro-Oncology: Strategies, Failures, and Challenges to Overcome

The blood-brain barrier (BBB) presents a formidable challenge in the development of effective therapeutics in neuro-oncology. This has fueled several decades of efforts to develop strategies for disrupting the BBB, but progress has not been satisfactory. As such, numerous drug- and device-based meth...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Karmur, Brij S., Philteos, Justine, Abbasian, Aram, Zacharia, Brad E., Lipsman, Nir, Levin, Victor, Grossman, Stuart, Mansouri, Alireza
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7531249/
https://ncbi.nlm.nih.gov/pubmed/33072591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.563840
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