TMOD-19. ELUCIDATING THE RESISTANCE TO IMMUNOTHERAPY IN BRAIN TUMORS USING A HUMANIZED MICROBIOME MOUSE MODEL

Although the immunotherapy anti-PD-1 works well in glioblastoma (GBM) pre-clinical mouse models, the therapy has not demonstrated a similar efficacy in patient clinical trials. Recent studies have linked the gut microbe composition to tumor growth and response to immunotherapy in some cancers. To da...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Dees, Kory, Koo, Hyunmin, Hakim, Joseph, Fraser Humphreys, J, Crossman, David, Crowley, Michael, Nabors, Louis, Benveniste, Etty, Morrow, Casey, McFarland, Braden
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Tumor Models
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846436/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1118
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