TMOD-19. INDIVIDUAL SPECIFIC HUMAN GUT MICROBE COMMUNITIES INFLUENCE RESPONSE TO IMMUNOTHERAPY IN A HUMANIZED MICROBIOME MOUSE MODEL OF GLIOMA

Although immunotherapy works well in glioblastoma (GBM) pre-clinical mouse models, the therapy has not demonstrated efficacy in GBM patients. Since recent studies have linked the gut microbial composition to the success with immunotherapy for other cancers, we utilized a novel humanized microbiome (...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Dees, Kory, Koo, Hyunmin, Humphreys, J Fraser, Hakim, Joseph, Crossman, David, Crowley, Michael, Nabors, Louis, Benveniste, Etty, Morrow, Casey, McFarland, Braden
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Tumor Models
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651034/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.970
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