TMOD-40. IN VIVO EVALUATION OF O(6)-METHYLGUANINE-DNA-METHYLTRANSFERASE (MGMT) PROMOTER METHYLATION STATUS FOR DE NOVO GLIOBLASTOMA PATIENTS USING DEEP LEARNING FEATURES

BACKGROUND: High expression of O6-methylguanine-DNA methyltransferase (MGMT) in glioblastoma is associated with resistance to temozolomide, as tumor cells lacking MGMT activity are significantly more sensitive to the cytotoxic effects of temozolomide. The MGMT promoter methylation status (MGMTpms) i...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Rathore, Saima, Nasrallah, MacLean, Akbari, Hamed, Shukla, Gaurav, Bagley, Stephen, Watt, Christopher, Min Ha, Sung, Mamourian, Elizabeth, Sako, Chiharu, Binder, Zev, O’Rourke, Donald, Davatzikos, Christos
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Tumor Models
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846190/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1139
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires