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TMOD-40. IN VIVO EVALUATION OF O(6)-METHYLGUANINE-DNA-METHYLTRANSFERASE (MGMT) PROMOTER METHYLATION STATUS FOR DE NOVO GLIOBLASTOMA PATIENTS USING DEEP LEARNING FEATURES

BACKGROUND: High expression of O6-methylguanine-DNA methyltransferase (MGMT) in glioblastoma is associated with resistance to temozolomide, as tumor cells lacking MGMT activity are significantly more sensitive to the cytotoxic effects of temozolomide. The MGMT promoter methylation status (MGMTpms) i...

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書誌詳細
出版年:Neuro Oncol
主要な著者: Rathore, Saima, Nasrallah, MacLean, Akbari, Hamed, Shukla, Gaurav, Bagley, Stephen, Watt, Christopher, Min Ha, Sung, Mamourian, Elizabeth, Sako, Chiharu, Binder, Zev, O’Rourke, Donald, Davatzikos, Christos
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846190/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1139
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