TMIC-64. THE ROLE OF TUMOR-DERIVED GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR (GM-CSF/CSF2) IN REGULATION OF MICROGLIA-DEPENDENT INVASION IN GLIOMAS

Brain resident immune cells (microglia) and peripheral macrophages accumulate in malignant gliomas and constitute for 30–50% of the tumor mass. These immune cells are polarized by factors released by glioma and become the pro-invasive, immunosuppressive cells that support tumor progression. We have...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Poleszak, Katarzyna, Pasierbinska, Maria, Ellert-Miklaszewska, Aleksandra, Wojtaś, Bartosz, Wojnicki, Kamil, Kaminska, Bozena
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Tumor Microenvironment
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845965/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1098
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