SCDT-28. THE SHORT PEPTIDE INTERFERING WITH GM-CSF BLOCKS GLIOMA-MICROGLIA INTERACTIONS AND ANTI-TUMOR EFFECTS ON ORTHOTOPIC U87 GLIOMAS IN NUDE MICE

Glioblastoma (WHO grade IV, GBM) is a malignant, very aggressive, primary brain tumor which due to tumor cell heterogeneity, genetic alterations and therapy resistance remains incurable. GBM is heavily infiltrated with microglia and macrophages which play an important role in proliferation, diffusiv...

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Vydáno v:Neuro Oncol
Hlavní autoři: Pasierbinska, Maria, Poleszak, Katarzyna, Kaminska, Bozena, Wisniewski, Pawel
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692017/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1111
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