SCDT-28. THE SHORT PEPTIDE INTERFERING WITH GM-CSF BLOCKS GLIOMA-MICROGLIA INTERACTIONS AND ANTI-TUMOR EFFECTS ON ORTHOTOPIC U87 GLIOMAS IN NUDE MICE

Glioblastoma (WHO grade IV, GBM) is a malignant, very aggressive, primary brain tumor which due to tumor cell heterogeneity, genetic alterations and therapy resistance remains incurable. GBM is heavily infiltrated with microglia and macrophages which play an important role in proliferation, diffusiv...

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Publicat a:Neuro Oncol
Autors principals: Pasierbinska, Maria, Poleszak, Katarzyna, Kaminska, Bozena, Wisniewski, Pawel
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692017/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1111
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