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SCDT-28. THE SHORT PEPTIDE INTERFERING WITH GM-CSF BLOCKS GLIOMA-MICROGLIA INTERACTIONS AND ANTI-TUMOR EFFECTS ON ORTHOTOPIC U87 GLIOMAS IN NUDE MICE

Glioblastoma (WHO grade IV, GBM) is a malignant, very aggressive, primary brain tumor which due to tumor cell heterogeneity, genetic alterations and therapy resistance remains incurable. GBM is heavily infiltrated with microglia and macrophages which play an important role in proliferation, diffusiv...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Pasierbinska, Maria, Poleszak, Katarzyna, Kaminska, Bozena, Wisniewski, Pawel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692017/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1111
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