Tumour-derived CSF2/granulocyte macrophage colony stimulating factor controls myeloid cell accumulation and progression of gliomas

BACKGROUND: Malignant tumours release factors, which attract myeloid cells and induce their polarisation to pro-invasive, immunosuppressive phenotypes. Brain-resident microglia and peripheral macrophages accumulate in the tumour microenvironment of glioblastoma (GBM) and induce immunosuppression fos...

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Publicado en:Br J Cancer
Autores principales: Sielska, Malgorzata, Przanowski, Piotr, Pasierbińska, Maria, Wojnicki, Kamil, Poleszak, Katarzyna, Wojtas, Bartosz, Grzeganek, Dominika, Ellert-Miklaszewska, Aleksandra, Ku, Min-Chi, Kettenmann, Helmut, Kaminska, Bozena
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7403321/
https://ncbi.nlm.nih.gov/pubmed/32390004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0862-2
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