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MTOR-DRIVEN ALTERATIONS IN THE BRAIN MICROVASCULAR PROTEOME IN ALZHEIMER’S DISEASE

Therapeutic interventions for Alzheimer’s disease (AD) remain limited due to an incomplete understanding of the molecular mechanisms of its onset and progression. Cerebrovascular dysfunction occurs early during disease development. Attenuation of mTOR, a key regulator of aging, attenuates and revers...

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Bibliografske podrobnosti
izdano v:Innov Aging
Main Authors: Banh, Andy, Pomilio, Carlos, Hussong, Stacy A, Galvan, Veronica
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845209/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.356
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