mTOR Attenuation with Rapamycin Reverses Neurovascular Uncoupling and Memory Deficits in Mice Modeling Alzheimer's Disease

Vascular dysfunction is a universal feature of aging and decreased cerebral blood flow has been identified as an early event in the pathogenesis of Alzheimer's disease (AD). Cerebrovascular dysfunction in AD includes deficits in neurovascular coupling (NVC), a mechanism that ensures rapid deliv...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Van Skike, Candice E., Hussong, Stacy A., Hernandez, Stephen F., Banh, Andy Q., DeRosa, Nicholas, Galvan, Veronica
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143195/
https://ncbi.nlm.nih.gov/pubmed/33888602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2144-20.2021
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