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Blocking late stages of splicing quickly limits pre-spliceosome assembly in vivo
Pre-messenger RNA splicing involves multi-step assembly of the large spliceosome complexes that catalyse the two consecutive trans-esterification reactions, resulting in intron removal. There is evidence that proof-reading mechanisms monitor the fidelity of this complex process. Transcripts that fai...
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| Publicado no: | RNA Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6844569/ https://ncbi.nlm.nih.gov/pubmed/31671032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1657788 |
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