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Is WDR45 the missing link for ER stress-induced autophagy in beta-propeller associated neurodegeneration?

Beta-propeller protein-associated neurodegeneration (BPAN) is caused by mutations in the autophagy gene WDR45/WIPI4. In human, BPAN is associated with static encephalopathy in childhood and neurodegeneration in adulthood (SENDA). It has been proposed that WDR45 mutations cause neurodegeneration due...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Mollereau, Bertrand, Walter, Ludivine
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844507/
https://ncbi.nlm.nih.gov/pubmed/31525124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1668229
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