HIF1A and NFAT5 coordinate Na(+)-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting

Infection and inflammation are able to induce diet-independent Na(+)-accumulation without commensurate water retention in afflicted tissues, which favors the pro-inflammatory activation of mouse macrophages and augments their antibacterial and antiparasitic activity. While Na(+)-boosted host defense...

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Detaylı Bibliyografya
Yayımlandı:Autophagy
Asıl Yazarlar: Neubert, Patrick, Weichselbaum, Andrea, Reitinger, Carmen, Schatz, Valentin, Schröder, Agnes, Ferdinand, John R., Simon, Michaela, Bär, Anna-Lorena, Brochhausen, Christoph, Gerlach, Roman G., Tomiuk, Stefan, Hammer, Karin, Wagner, Stefan, van Zandbergen, Ger, Binger, Katrina J., Müller, Dominik N., Kitada, Kento, Clatworthy, Menna R., Kurts, Christian, Titze, Jens, Abdullah, Zeinab, Jantsch, Jonathan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2019
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844503/
https://ncbi.nlm.nih.gov/pubmed/30982460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1596483
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