Osteoprotective action of low-salt diet requires myeloid cell–derived NFAT5

Dietary salt consumption leads to cutaneous Na(+) storage and is associated with various disorders, including osteopenia. Here, we explore the impact of Na(+) and the osmoprotective transcription factor nuclear factor of activated T cell 5 (NFAT5) on bone density and osteoclastogenesis. Compared wit...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Schröder, Agnes, Neubert, Patrick, Titze, Jens, Bozec, Aline, Neuhofer, Wolfgang, Proff, Peter, Kirschneck, Christian, Jantsch, Jonathan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962031/
https://ncbi.nlm.nih.gov/pubmed/31801906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127868
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