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Directed C(sp(3))–H arylation of tryptophan: transformation of the directing group into an activated amide
The 8-aminoquinoline (8AQ) directed C(sp(3))–H functionalization was applied in the synthesis of β-arylated tryptophan derivatives. The laborious protecting group reorganization towards α-amino acids compatible for solid phase peptide synthesis (SPPS) was cut short by the transformation of the direc...
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| Publicado en: | Chem Sci |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6844298/ https://ncbi.nlm.nih.gov/pubmed/31803437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc03440d |
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