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Cytotoxicity Of Chalcone Of Eugenia aquea Burm F. Leaves Against T47D Breast Cancer Cell Lines And Its Prediction As An Estrogen Receptor Antagonist Based On Pharmacophore-Molecular Dynamics Simulation
BACKGROUND: The 2ʹ,4ʹ-dihydroxy-6-methoxy-3,5-3-dimethylchalcone (ChalcEA) isolated from Eugenia aquea Burm f. leaves has potential anticancer activity against human breast-adenocarcinoma cell lines (MCF-7) with an IC(50) value of 250 µM. However, its apoptotic activity on the T47D breast cancer cel...
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| Publicat a: | Adv Appl Bioinform Chem |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Dove
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6844098/ https://ncbi.nlm.nih.gov/pubmed/31807030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/AABC.S217205 |
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